Effect of a chlorhexidine-encapsulated nanotube modified pit-and-fissure sealant on oral biofilm

The purpose of this study was to characterize a chlorhexidine-encapsulated nanotube modified pit-and-fissure sealant for biofilm development prevention. HS (commercial control); HNT (HS+15wt%Halloysite®-clay-nanotube); CHX10% (HS+15wt% HNT-encapsulated with chlorhexidine 10%); and CHX20% CHX20%) were tested. Degree-of-conversion (DC%), Knoop hardness (KHN), viscosity analyzed. ability the wet fissures evaluated. Specimens tested zones inhibition microbial growth. S. mutans by measuring recovered viability. Data statistically analyzed (p<0.05). DC% significantly higher HNT-CHX groups. For KHN, presented lower mean value than other Adding resulted in values. on sealants remarkable CFU/mL reduction comparison HS. experimental material able reduce without compromising properties.